Journal: International Journal of Molecular Sciences

Article Title: Uncovering a Phenomenon of Active Hormone Transcriptional Regulation during Early Somatic Embryogenesis in Medicago sativa

doi: 10.3390/ijms23158633

Figure Lengend Snippet: Unigene and small RNA length distributions. ( a ) Unigenes and transcriots; ( b ) Small RNAs.

Article Snippet: More than 92.89% of miRNAs had multiple target unigenes, and only 29 miRNAs (7.11%) had a single unigene or no unigene from all miRNA–target gene pairs.

Techniques:

Journal: Stem Cells and Development

Article Title: Alleviating GAA Repeat Induced Transcriptional Silencing of the Friedreich's Ataxia Gene During Somatic Cell Reprogramming

doi: 10.1089/scd.2016.0147

Figure Lengend Snippet: Miniscreen for Epigenetic Regulators of FXN Silencing During Reprogramming

Article Snippet: DMSO, dimethyl sulfoxide; NaB, sodium butyrate; OSKM, Oct3/4, Sox2, Klf4, c-myc transcription factors. table ft1 table-wrap mode="anchored" t5 Table 1. caption a7 Compound (abbreviation) Target Process Concentration HDAC inhibitor 4b (4b) a HDAC3 Histone acetylation 5 μM Sodium butyrate (NaB) HDAC class I Histone acetylation 0.5 mM Tranylcypromine, Parnate (Par) LSD1 Histone H3K4 methylation 4 μM Tubastatin A (TubA) HDAC6 Histone acetylation 5 μM RG108 (RG) DNMT CpG methylation 5 μM BIX01294 (BIX) G9a Histone H3K9 methylation 4 μM Epi-ML (EML) b Multiple Multiple targets 5 μM DMSO Control — — Open in a separate window Only compounds that resulted in successful establishment of iPSC clones are shown. a HDACi 4b has been demonstrated to increase expression of the FXN gene in FRDA lymphoid cells and neurons, but not in FRDA fibroblasts or iPSCs. b Epigenetic Multiple Ligand (Epi-ML; Calbiochem) is a cell-permeable bis -arylidene compound that inhibits several mammalian histone-modifying enzymes, including SET7, PRMT1, p300/CBP, and SIRT1/2.

Techniques: Concentration Assay, Methylation, CpG Methylation Assay

Journal: European Heart Journal: Case Reports

Article Title: A rare presentation of mycotic cerebral aneurysm, subarachnoid haemorrhage, and mitral valve aneurysm in left-sided lnfective endocarditis: a case report and literature review

doi: 10.1093/ehjcr/ytad567

Figure Lengend Snippet:

Article Snippet: Computed tomography (CT) angiogram with cerebral embolization. The aneurysm in the middle cerebral artery branch, including the parent vessel, was occluded using multiple target detachable coils (Stryker, USA)..

Techniques: Biomarker Discovery, Computed Tomography